치아재생을 위한 계승치 형성 신호전달체계의 이해
Implications of principles in successional teeth formation on tooth regeneration
김태영, 포카렐 엘리나, 이승준, 구건우, 권순규, 김지현, 이정훈, 전성욱, 채민제, 이영균, 안창현, 김재영,
소속 상세정보
김태영 ( Kim Tae-Young ) - Kyungpook National University School of Dentistry Department of Biochemistry
포카렐 엘리나 ( Pokharel Elina ) - Kyungpook National University School of Dentistry Department of Biochemistry
이승준 ( Lee Seung-Jun ) - Kyungpook National University School of Dentistry Department of Biochemistry
구건우 ( Ku Gun-Woo ) - Kyungpook National University School of Dentistry Department of Biochemistry
권순규 ( Kwon Soon-Gyu ) - Kyungpook National University School of Dentistry Department of Biochemistry
김지현 ( Kim Ji-Hyeon ) - Kyungpook National University School of Dentistry Department of Biochemistry
이정훈 ( Lee Jung-Hoon ) - Kyungpook National University School of Dentistry Department of Biochemistry
전성욱 ( Jeon Seong-Uk ) - Kyungpook National University School of Dentistry Department of Biochemistry
채민제 ( Chae Min-Jae ) - Kyungpook National University School of Dentistry Department of Biochemistry
이영균 ( Lee Young-Kyun ) - Kyungpook National University School of Dentistry Department of Biochemistry
안창현 ( An Chang-Hyeon ) - Kyungpook National University School of Dentistry Department of Oral and Maxillofacial Radiology
김재영 ( Kim Jae-Young ) - Kyungpook National University School of Dentistry Department of Biochemistry
KMID : 0355820220430010087
Abstract
치아재생을 위한 다양한 분야의 연구가 진행되고 있지만 구조적 기능적 재생을 위한 실질적인 연구결과물의 생산에는 한계가 있는 실정이다. 본 논문에서는 계승치의 형성에 관련된 기존 연구들에 대해 확인하고 이를 통해 치아 재생을 위한 새로운 개념의 연구에 대해 소개하고자 한다. 이를 통해 실질적인 치아 경조직 및 치아 자체의 재생을 위한 계기를 마련하고자 한다.
Various studies on tooth regeneration have been conducted. However, there are still no proper applications in the clinical field. This study suggests new conceptual approaches to dental hard tissue regeneration using analyzation and utilization of successional teeth formation. Polyphydontic species, such as reptiles and fish, have a unique signal transmission system in which teeth are replaced throughout life. Based on these observations, we analyze the signal transmission systems related to these specific teeth formations for regenerating dental hard tissue. Overall, this study would provide an opportunity to use these candidate signalings as blueprints for tooth regeneration by comparing them to normal teeth development.
키워드
계승치; 신호전달경로; 재생
successional tooth; signaling pathway; regeneration
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